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Radionuclide voiding pattern in children with unstable bladder

M Vlajković1, M Bogicević, M Rajić

  • 1Department of Nuclear Medicine, Clinical Center, Nis, Yugoslavia.

Nuclear Medicine Review. Central & Eastern Europe
|November 6, 2003
PubMed

Insights

Quantitative radionuclide cystography (QRC) effectively differentiates unstable bladder in children. This noninvasive method assesses bladder function, revealing significant differences in capacity and voiding dynamics compared to healthy controls.

Area of Science:

  • Pediatric Urology
  • Diagnostic Imaging
  • Nuclear Medicine

Background:

  • Unstable bladder is a common condition in anxious, irritable children.
  • Assessing bladder function in pediatric patients is crucial for diagnosis and management.

Purpose of the Study:

  • To investigate bladder function parameters using quantitative radionuclide cystography (QRC).
  • To evaluate the efficacy of QRC in distinguishing children with unstable bladder from healthy controls.

Main Methods:

  • QRC was performed on 18 children (8-12 years) with unstable bladder and 10 healthy children (7-10 years).
  • 99mTc-diethylenetriaminepentaacetic acid (DTPA) was administered intravenously to assess bladder emptying dynamics.
  • Voiding images were captured, and parameters like functional bladder capacity (FBC), voided urine volume (VV), and residual urine (RU) were measured.

Main Results:

  • Children with unstable bladder showed significantly lower FBC, % of expected bladder capacity (EBC), and VV compared to controls.
  • Significantly higher residual urine (RU) was observed in children with unstable bladder.
  • Average flow rate (AFR) and peak flow rate (PFR) were significantly lower in the unstable bladder group, while voiding time (VT) did not differ significantly.

Conclusions:

  • Quantitative radionuclide cystography (QRC) is a simple and noninvasive diagnostic tool.
  • QRC effectively differentiates children with unstable bladder from those with normal voiding patterns.
  • The study highlights QRC's utility in pediatric urology for assessing bladder dysfunction.
Abstract

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