Global, regional and national perinatal and neonatal mortality

Victor Y Yu1

  • 1Department of Paediatrics, Ritchie Centre for Baby Health Research, Monash University, Melbourne, Australia. victor.yu@med.monash.edu.au

Insights

Global perinatal mortality remains high, especially in developing nations. Addressing health inequalities is crucial for improving outcomes for mothers and newborns worldwide.

Area of Science:

  • Global Health
  • Perinatal Medicine
  • Neonatal Health

Background:

  • High global perinatal mortality rate (PMR) of 53/1000 and neonatal mortality rate (NMR) of 36/1000, with 7.5 and 5.1 million deaths annually, respectively.
  • Developing countries bear the brunt, with significantly higher PMR (57/1000) and NMR (39/1000) compared to developed nations, accounting for 90% of livebirths and 98% of neonatal deaths.
  • The Asia-Oceania region faces a disproportionately high burden, contributing half of the world's livebirths and two-thirds of neonatal deaths.

Purpose of the Study:

  • To highlight the disparities in perinatal and neonatal mortality rates globally.
  • To underscore the role of PMR and NMR as indicators of healthcare system quality.
  • To emphasize the need for strategies addressing national and international inequalities to improve perinatal health.

Main Methods:

  • Analysis of global, regional, and national perinatal and neonatal mortality statistics.
  • Comparison of mortality rates between developing and developed countries.
  • Examination of livebirth and neonatal death distribution across continents.

Main Results:

  • Developing countries experience 5.2x higher PMR and 5.6x higher NMR than developed countries.
  • Asia-Oceania reports a PMR of 53/1000 and NMR of 41/1000, with substantial numbers of births and deaths.
  • Significant regional variations exist in livebirths and neonatal deaths, with Asia-Oceania and Africa having the highest figures.

Conclusions:

  • Perinatal and neonatal mortality rates are critical indicators of socioeconomic and healthcare system performance.
  • Urgent interventions are required to reduce the high burden of perinatal and neonatal deaths in developing countries.
  • Addressing health inequalities within and between countries is paramount for achieving global improvements in perinatal health.

Related Concept Videos

International Nursing Organizations II01:28

International Nursing Organizations II

The World Health Organization (WHO) is a specialized agency of the United Nations based in Geneva. The WHO has many initiatives that center around health. Primarily, they lead global efforts to expand universal health coverage using science-based policies and programs. They are also responsible for shaping health research agendas and developing norms and standards.
The WHO provides expert team support, including funding, vaccines, testing, and treatment tools at the country level to fight...
Teratogenicity01:07

Teratogenicity

The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
Development of the Oral Microbiota01:28

Development of the Oral Microbiota

The establishment of the oral microbiome begins before birth, challenging the long-held belief that the fetal oral cavity is sterile. The presence of oral microbes such as Streptococcus and Fusobacterium in amniotic fluid suggests that microbial exposure may occur in utero, potentially through translocation from the maternal oral or gastrointestinal tract. This early colonization primes the neonatal immune system and sets the stage for subsequent microbial succession. Maternal health,...