Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Alzheimer's disease.

L S Honig1, S S Chin

  • 1Columbia University College of Physicians and Surgeons, Taub Institute for Research on Alzheimer's Disease and the Aging Brain, The Alzheimer's Disease Research Center, Department of Neurology, New York, NY 10032, USA. lh456@columbia.edu

Science of Aging Knowledge Environment : SAGE KE
|November 7, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Dominantly Inherited Alzheimer Network Trials Unit (DIAN-TU): Trial Satisfaction and Attitudes towards Future Clinical Trials.

The journal of prevention of Alzheimer's disease..·2024
Same author

Effects of Vascular Risk Factors on the Association of Blood-Based Biomarkers with Alzheimer's Disease.

Medical research archives·2023
Same author

A Randomized, Double-Blind, Phase 2 Study of the Effects of the Vaccine Vanutide Cridificar with QS-21 Adjuvant on Immunogenicity, Safety and Amyloid Imaging in Patients with Mild to Moderate Alzheimer's Disease.

The journal of prevention of Alzheimer's disease·2017
Same author

Extracellular Tau Oligomers Produce An Immediate Impairment of LTP and Memory.

Scientific reports·2016
Same author

Increased number of Purkinje cell dendritic swellings in essential tremor.

European journal of neurology·2011
Same author

Pituicytoma, spindle cell oncocytoma, and granular cell tumor: clarification and meta-analysis of the world literature since 1893.

AJNR. American journal of neuroradiology·2011
Same journal

I come not to bury SAGE KE but to appraise It.

Science of aging knowledge environment : SAGE KE·2006
Same journal

Targeting the role of the endosome in the pathophysiology of Alzheimer's disease: a strategy for treatment.

Science of aging knowledge environment : SAGE KE·2006
Same journal

From bedside to bench: does mental and physical activity promote cognitive vitality in late life?

Science of aging knowledge environment : SAGE KE·2006
Same journal

The unusual genetics of human longevity.

Science of aging knowledge environment : SAGE KE·2006
Same journal

A work in progress: the metabolic syndrome.

Science of aging knowledge environment : SAGE KE·2006
Same journal

WRN's tenth anniversary.

Science of aging knowledge environment : SAGE KE·2006
See all related articles

This case study details Alzheimer's disease (AD) in a patient with prominent language deficits. Brain pathology revealed characteristic senile plaques and neurofibrillary tangles.

Area of Science:

  • Neurology
  • Neuroscience
  • Pathology

Background:

  • Alzheimer's disease (AD) is a progressive neurodegenerative disorder.
  • AD typically affects memory and language functions.
  • Pathological hallmarks include senile plaques and neurofibrillary tangles.

Observation:

  • This case study focuses on a male patient diagnosed with Alzheimer's disease.
  • The patient presented with notable language difficulties, more pronounced than memory impairment.
  • Neuropsychological testing was conducted to assess cognitive deficits.

Findings:

  • The patient exhibited significant language dysfunction.
  • Memory impairment was less prominent compared to language deficits.
  • Post-mortem brain examination revealed widespread senile plaques and neurofibrillary tangles in the limbic system and neocortex.

Related Experiment Videos

Implications:

  • This case highlights the variability in Alzheimer's disease symptom presentation.
  • Understanding atypical presentations is crucial for accurate diagnosis.
  • The findings reinforce the neuropathological basis of Alzheimer's disease.