Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Microthrombectomy reduces postsclerotherapy pigmentation: multicenter randomized trial.

Anke H Scultetus1, J Leonel Villavicencio, Tzu-Cheg Kao

  • 1Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA.

Journal of Vascular Surgery
|November 7, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Risk of First Adjustment Disorder in U.S. Army Soldiers.

Military medicine·2026
Same author

Correction: Feasibility and reliability of a smartwatch to detect atrial fibrillation after cardiac surgery: a prospective study.

Frontiers in digital health·2026
Same author

Drama-based simulations in first aid education: psychometric validation of a student assessment tool in school settings.

Frontiers in public health·2026
Same author

Hybrid durable biventricular assist device implantation with Berlin Heart EXCOR pulsatile RVAD and a continuous flow LVAD.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation·2026
Same author

Long-term left ventricular assist device support reinforces detrimental immunological effects.

Frontiers in immunology·2026
Same author

Feasibility and reliability of a smartwatch to detect atrial fibrillation after cardiac surgery: a prospective study.

Frontiers in digital health·2026

Early microthrombectomy significantly reduced post-sclerotherapy pigmentation in smaller veins. This procedure also improved overall clinical outcomes and reduced pain and inflammation, making it a recommended treatment.

Area of Science:

  • Vascular Surgery
  • Dermatology
  • Phlebology

Background:

  • Postsclerotherapy pigmentation, a common complication, is linked to hemosiderin deposition from venous thrombus.
  • The efficacy of early microthrombectomy in preventing or reducing this pigmentation remains unproven.

Purpose of the Study:

  • To evaluate the impact of early microthrombectomy on the incidence of postsclerotherapy pigmentation.
  • To assess the effect of microthrombectomy on overall clinical improvement and patient-reported outcomes.

Main Methods:

  • A multicenter, randomized controlled study involving 101 patients with varicose veins treated with Sotradecol.
  • Patients were divided into two groups based on vein diameter (≤1 mm or ≤3 mm).
  • Microthrombectomy was performed 1-3 weeks post-sclerotherapy on one half of the treated varicosities, with the other half serving as a control.

Related Experiment Videos

Main Results:

  • In veins ≤1 mm, microthrombectomy significantly reduced pigmentation (P=.0047) and improved clinical scores (P=.0002).
  • In veins ≤3 mm, no significant difference in pigmentation was observed, but patients reported reduced pain and inflammation.

Conclusions:

  • Early microthrombectomy is effective in decreasing postsclerotherapy pigmentation and enhancing clinical results in smaller veins (≤1 mm).
  • While not achieving statistical significance for pigmentation in larger veins (≤3 mm), microthrombectomy aids in faster resolution of post-sclerotherapy complications like pain and inflammation.
  • Microthrombectomy is recommended as an adjunct to sclerotherapy.