Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cardioventilatory coupling in resting human subjects.

Y C Tzeng1, P D Larsen, D C Galletly

  • 1Department of Surgery and Anesthesia, Wellington School of Medicine and Health Sciences, PO Box 7343, Wellington, New Zealand. shieak@slingshot.co.nz

Experimental Physiology
|November 7, 2003
PubMed
Summary

Cardioventilatory coupling, the synchronization of heartbeats and breathing, was found in most conscious individuals. This physiological link influences heart rate and respiratory frequency ratios.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Rebuttal from Y. C. Tzeng and R. B. Panerai.

The Journal of physiology·2017
Same author

CrossTalk proposal: dynamic cerebral autoregulation should be quantified using spontaneous blood pressure fluctuations.

The Journal of physiology·2017
Same author

Pacemaker Use in New Zealand - Data From the New Zealand Implanted Cardiac Device Registry (ANZACS-QI 15).

Heart, lung & circulation·2016
Same author

Interactions between breathing rate and low-frequency fluctuations in blood pressure and cardiac intervals.

Journal of applied physiology (Bethesda, Md. : 1985)·2015
Same author

Prasugrel inhibits platelet-enhanced pro-inflammatory CD4+ T cell responses in humans.

Atherosclerosis·2015
Same author

Prevalence and significance of CYP2C19*2 and CYP2C19*17 alleles in a New Zealand acute coronary syndrome population.

Internal medicine journal·2015

Area of Science:

  • Physiology
  • Autonomic Nervous System Function

Background:

  • Cardioventilatory coupling, the synchronization between heartbeats and breathing, has been previously observed in anesthetized subjects.
  • Understanding this coupling in conscious individuals is crucial for respiratory control research.

Purpose of the Study:

  • To investigate the temporal coupling between heart beat timing and inspiration onset (cardioventilatory coupling) in conscious resting subjects.
  • To explore the relationship between cardioventilatory coupling and spectral indices of autonomic function.

Main Methods:

  • Utilized proportional Shannon entropy (SH(alpha)) of the RI(-1) interval to quantify cardioventilatory coupling.
  • Analyzed time series plots of RI intervals for visual confirmation of coupling.
  • Assessed spectral indices of autonomic function, including heart rate variability and blood pressure variability.

Related Experiment Videos

Main Results:

  • Statistically significant cardioventilatory coupling was detected in 32 out of 48 conscious subjects.
  • Coupling was associated with a preference for whole number heart rate/respiratory frequency ratios.
  • Strongest coupling correlated with low ventilatory frequency and high heart rate variability, but not blood pressure variability or baroreflex sensitivity.

Conclusions:

  • Cardioventilatory coupling, similar to that observed during anesthesia, is present in conscious individuals.
  • The findings suggest a significant role for cardioventilatory coupling in physiological respiratory control.
  • Further research is warranted to fully explore the implications of this coupling.