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Aging or osteoarthritis: which is the problem?

Richard F Loeser1, Najia Shakoor

  • 1Section of Rheumatology, Rush Medical College, Rush-Presbyterian-St. Luke's Medical Center, 1725 West Harrison, Suite 1017, Chicago, IL 60612, USA. rloeser@rush.edu

Rheumatic Diseases Clinics of North America
|November 8, 2003
PubMed
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Osteoarthritis (OA) is not an inevitable part of aging. Managing joint pain in older adults should focus on improving neuromuscular function and preventing further declines, as medications for OA progression are unavailable.

Area of Science:

  • Gerontology
  • Musculoskeletal Health
  • Biomedical Engineering

Background:

  • Aging-related musculoskeletal changes increase osteoarthritis (OA) risk when combined with other factors.
  • Joints function as biomechanical units within the neuromuscular system.
  • Factors contributing to joint pain and dysfunction include aging, musculoskeletal underuse/misuse, and OA development.

Purpose of the Study:

  • To explore the multifactorial nature of joint pain and loss of function in older adults.
  • To investigate the relationship between aging, musculoskeletal health, and osteoarthritis.
  • To identify optimal management strategies for older adults experiencing joint pain and functional decline.

Main Methods:

  • Review of existing literature on aging, musculoskeletal system, and osteoarthritis.

Related Experiment Videos

  • Analysis of the interplay between neuromuscular function, strength, balance, and proprioception.
  • Examination of the correlation between radiographic OA findings and reported pain/disability.

    • Main Results:

    • Osteoarthritis is not an inevitable outcome of aging; aging-related musculoskeletal changes elevate risk with co-existing factors.
    • Complex interactions exist among aging, underuse, and OA, affecting strength, balance, and proprioception.
    • Radiographic evidence of OA does not always correlate with observed pain and disability in older adults.

    Conclusions:

    • Management for older adults with joint pain and functional loss should prioritize enhancing neuromuscular function.
    • Preventing further declines in neuromuscular function is crucial in the absence of OA progression-halting pharmacologic agents.
    • Focusing on biomechanical and neuromuscular aspects offers a viable strategy for managing OA-related symptoms.