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Related Experiment Videos

ASD closure with the Amplatzer device.

Horacio J Faella1, Alberto M Sciegata, José L Alonso

  • 1Department of Interventional Cardiology, Garrahan Children's Hospital, Buenos Aires, Argentina. homefaella@sion.com

Journal of Interventional Cardiology
|November 8, 2003
PubMed
Summary
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The Amplatzer Septal Occluder (ASO) device effectively closes atrial septal defects (ASDs) and fenestrated Fontan in patients of all ages. This transcatheter approach demonstrates high closure rates with minimal complications, offering a safe alternative to surgery.

Area of Science:

  • Cardiovascular Medicine
  • Interventional Cardiology
  • Pediatric Cardiology

Background:

  • Atrial septal defects (ASDs) and fenestrated Fontan present significant challenges in pediatric and adult cardiology.
  • Transcatheter closure offers a less invasive alternative to surgical repair for these conditions.

Purpose of the Study:

  • To evaluate the safety and efficacy of the Amplatzer Septal Occluder (ASO) device.
  • To assess the device's performance in transcatheter closure of secundum ASDs and fenestrated Fontan procedures.

Main Methods:

  • A retrospective analysis of 102 patients undergoing transcatheter closure with the ASO device.
  • Echocardiography (TEE) was used to determine defect size and assess shunt post-procedure.
  • Patient demographics, procedural details, and complication rates were recorded.

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Main Results:

  • The median patient age was 18.2 years, with a median ASD size of 17.6 mm.
  • Immediate post-procedure, 90.19% of patients had no residual shunt; 100% closure was achieved at 24 hours.
  • Minor complications included atrial arrhythmias in 4 patients; one major complication resulted in mortality.

Conclusions:

  • The ASO device is a safe and effective option for the transcatheter closure of most secundum ASDs.
  • The device is also effective for fenestrated Fontan procedures, demonstrating high closure rates and an acceptable safety profile.