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Updated: Aug 30, 2026

A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer
Published on: March 6, 2018
Current problems of prostate cancer
F Goncalves1, M Hornak, D Ondrus
1Department of Urology, Faculty ofMedicine, Comenius University, Derer's Memorial Hospital, Bratislava, Slovakia. bll@fmed.uniba.sk
Abstract:
Metastatic prostate cancer is primarily treated by endocrine manipulation. Complete androgen blockade with analogue of luteinizing hormone releasing hormone (LHRH) or surgical castration and antiandrogens seem to have no advantage over the LHRH analogues or surgical castration alone. The progression to a hormone-refractory state is still a challenging issue for urologists because of the lack of standard therapy.
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