Frosted branch angiitis in two Chinese young girls

We examined 2 relatively healthy young girls who presented with acute red eyes and blurred vision. Each patient developed thick, inflammatory infiltrates surrounding the retinal vessels creating the appearance of frosted tree branches in both eyes. Marked inflammatory reactions with cells and flare were noted in anterior chambers. One patient even had hypopyon in both eyes. Initial visual acuity ranged from 6/6.7 to 6/60. Both patients showed rapid improvement with systemic and/or topical corticosteroid therapy, and all of the affected eyes regained a visual acuity of 6/6. The clinical appearances and courses of these two patients matched the condition previously described in Japan and labeled frosted branch angiitis. Before this article, there was only one case reported in Taiwan.