Related Experiment Video

Updated: Jul 31, 2026

A Soluble Tetrazolium-Based Reduction Assay to Evaluate the Effect of Antibodies on Candida tropicalis Biofilms
06:50

A Soluble Tetrazolium-Based Reduction Assay to Evaluate the Effect of Antibodies on Candida tropicalis Biofilms

Published on: September 16, 2022

[Candida parapsilosis endocarditis after prolonged antibiotic therapy]

A Castillo Caparrós1, A M Montijano Cabrera

  • 1Servicio de Anestesiología y Reanimación, Hospital Clínico-Universitario Virgen de la Victoria de Málaga. acastilloc@medynet.com

Revista Espanola De Anestesiologia Y Reanimacion
|November 11, 2003
PubMed

Insights

Infective endocarditis caused by Candida parapsilosis can be fatal, even with prompt treatment. This case highlights the risks of fungal infections following prolonged antibiotic use.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Mycology

Background:

  • Infective endocarditis (IE) remains a serious condition with improved prognoses due to advanced technologies.
  • However, increased fungal growth and more virulent forms are contributing to a rise in cases.
  • Prolonged intravenous antibiotic treatment can be a risk factor for opportunistic infections.

Observation:

  • A case of endocarditis caused by Candida parapsilosis is presented.
  • The infection occurred on a previously healthy aortic valve in a male patient.
  • The patient had a history of prolonged intravenous antibiotic treatment a few months prior.

Findings:

  • The initial presentation was acute arterial ischemia of the lower limbs.
  • Diagnosis was confirmed via echocardiography and microbiology.
  • Despite antifungal therapy, embolectomy, and valve replacement, the infection was uncontrollable.

Implications:

  • This case underscores the potential severity of Candida parapsilosis endocarditis.
  • It highlights the risk of invasive fungal infections after extensive antibiotic therapy.
  • Aggressive management may not always prevent fatal outcomes in severe fungal endocarditis.

More Related Videos

A Periprosthetic Joint Candida albicans Infection Model in Mouse04:37

A Periprosthetic Joint Candida albicans Infection Model in Mouse

Published on: February 2, 2024

A Catheter-Related Candida albicans Infection Model in Mouse03:24

A Catheter-Related Candida albicans Infection Model in Mouse

Published on: March 22, 2024

Related Concept Videos

Endocarditis I: Introduction01:25

Endocarditis I: Introduction

Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
Endocarditis III: Medical Management01:18

Endocarditis III: Medical Management

Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
Endocarditis IV: Nursing Management01:29

Endocarditis IV: Nursing Management

Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...
Myocarditis III: Medical Management01:14

Myocarditis III: Medical Management

Myocarditis: Comprehensive Medical ManagementMyocarditis, the heart muscle inflammation, requires a comprehensive medical management strategy that addresses the underlying cause, provides supportive care, manages symptoms, and reduces cardiac workload.Infections and Autoimmune CausesAdminister appropriate antimicrobial therapy when an infectious agent causes myocarditis. For instance, penicillin treats infections caused by Group A Streptococcus. In cases where autoimmune processes are...
Cryptococcal Meningitis01:27

Cryptococcal Meningitis

Cryptococcal meningitis is a life-threatening opportunistic infection predominantly associated with HIV/AIDS, accounting for over 100,000 deaths annually worldwide. However, it also affects individuals with other forms of immunosuppression, including those undergoing immunosuppressive therapy, organ transplant recipients, patients with innate immunodeficiencies, and individuals with hematological disorders. The infection is caused mainly by Cryptococcus neoformans and Cryptococcus gattii,...
Candidiasis01:20

Candidiasis

Candidiasis is a fungal infection caused by opportunistic species of Candida. It can affect various anatomical sites, including the skin, oral cavity, nails, and genitourinary tract. Among its forms, vaginal candidiasis is the most common type of mucosal infection. It typically results from the overgrowth of Candida albicans in the vaginal mucosa. Under normal conditions, C. albicans exists as a commensal organism within the vaginal microbiota, regulated by the dominance of lactobacilli, which...