Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Attenuation coefficient measurement in the thyroid.

Yasutomo Fujii1, Nobuyuki Taniguchi, Kouichi Itoh

  • 1Department of Clinical Laboratory Medicine, Jichi Medical School, Tochigi, Japan. yfujii@jichi.ac.jp

Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine
|November 11, 2003
PubMed
Summary

A new method for measuring thyroid attenuation coefficients shows reduced variability compared to conventional techniques. This novel approach is feasible for in vivo thyroid evaluation, differentiating normal from diseased states.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Identification of the collecting lymphatic vessel responsible for dermal backflow using indocyanine green lymphography-guided contrast-enhanced ultrasound.

Journal of vascular surgery. Venous and lymphatic disorders·2026
Same author

C-C motif chemokine 3 interferes with oligodendrocyte maturation in the brain.

Biochemical and biophysical research communications·2026
Same author

Prevalence of Significant Coronary Artery Stenosis and Relationship with Carotid Maximum Intima-Media Thickness in Asymptomatic Patients with Moderate-to-Severe Chronic Kidney Disease: A Single-Center, Prospective, Cross-Sectional Study.

Vascular health and risk management·2025
Same author

Routine Laboratory Tests Predict 72-h Fatality in Patients With D-Dimer Levels ≥ 2 μg/mL: A Retrospective Cohort Study Comparing Statistical and Machine Learning Models.

Journal of clinical laboratory analysis·2025
Same author

Protocol and Progress of a Thyroid Study in the Epidemiological Study of Health Effects in Fukushima Emergency Workers.

Disaster medicine and public health preparedness·2025
Same author

Predicting 72-Hour Fatality in Severe Hyperphosphatemia: A Comparative Analysis of Multivariate Logistic Regression and Machine Learning Models in a Single-Center Study.

Cureus·2025

Area of Science:

  • Ultrasound physics
  • Medical imaging
  • Thyroid diagnostics

Background:

  • Thyroid disease diagnosis relies on imaging techniques.
  • Accurate measurement of tissue properties like attenuation coefficient is crucial.
  • Conventional methods for measuring thyroid attenuation coefficient exhibit significant variability.

Purpose of the Study:

  • To evaluate the feasibility of a novel method for measuring thyroid attenuation coefficient.
  • To compare the variability of the novel method with conventional techniques.
  • To assess the diagnostic potential of the novel method in differentiating thyroid conditions.

Main Methods:

  • A new ultrasound-based method was developed to calculate the attenuation coefficient with sound field correction.

Related Experiment Videos

  • The novel method's equation: alpha = -1/4[Fc(z)-epsilon(z)] x d/dz[log(M0(z))-tau(z)].
  • Simultaneous evaluation using the spectral shift central frequency method was performed on 32 normal thyroids, 26 Graves' disease, and 11 Hashimoto thyroiditis cases.

    • Main Results:

    • The novel method yielded mean attenuation coefficients: 1.50 ± 0.26 dB·cm⁻¹·MHz⁻¹ (normal), 0.91 ± 0.23 dB·cm⁻¹·MHz⁻¹ (Graves'), and 1.10 ± 0.27 dB·cm⁻¹·MHz⁻¹ (Hashimoto's).
    • Statistically significant differences were observed between normal and diseased thyroids (P < .0001) and between Graves' and Hashimoto's groups (P = .0035).
    • The novel method demonstrated significantly lower statistical variation compared to the spectral shift method across all groups.

    Conclusions:

    • The novel method is feasible for in vivo thyroid attenuation coefficient evaluation.
    • This technique offers reduced result variability compared to conventional methods.
    • The method shows promise for differentiating thyroid pathologies.