Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Apoptosis in yeasts.

Martin Weinberger1, Lakshmi Ramachandran, William C Burhans

  • 1Dept. of Cancer Genetics and Biophysical Therapies Program, Roswell Park Cancer Institute, Buffalo, NY 14263, USA.

IUBMB Life
|November 12, 2003
PubMed
Summary

Yeasts can undergo apoptosis, a programmed cell death, when triggered by DNA damage. This makes them a valuable model for studying cancer therapeutics and DNA damage responses.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Exploring the 4D printing linked bio-smart materials in dentistry: a concise overview.

Frontiers in dental medicine·2025
Same author

Horizontal platelet-rich fibrin versus advanced platelet-rich fibrin plus in gingival recession management.

Clinical advances in periodontics·2025
Same author

Advanced platelet-rich fibrin versus connective tissue graft in maxillary gingival recession management.

Clinical advances in periodontics·2024
Same author

Navigating Oral Hygiene Challenges in Spastic Cerebral Palsy Patients: A Narrative Review for Management Strategies for Optimal Dental Care.

Cureus·2024
Same author

Comparison of the Clinical Efficacy of Bioresorbable Xenogeneic Peritoneal Membrane vs Connective Tissue Graft in the Management of Gingival Recession Defects: A Randomized Controlled Clinical Trial.

The International journal of periodontics & restorative dentistry·2023
Same author

Clinical evaluation of the combined efficacy of injectable platelet-rich fibrin along with scaling and root planing in the non-surgical periodontal therapy of stage III and grade C periodontitis patients having type 2 diabetes mellitus: A randomized controlled trial.

Clinical advances in periodontics·2023

Area of Science:

  • Cell Biology
  • Molecular Biology
  • Genetics

Background:

  • Metazoan apoptosis involves complex machinery.
  • Yeasts possess some, but not all, apoptotic components.
  • Recent studies indicate apoptosis can be induced in yeasts.

Purpose of the Study:

  • To summarize recent findings on yeast apoptosis.
  • To explore the implications of yeast apoptosis for drug development.
  • To highlight yeast as a model for DNA damage and cell cycle regulation.

Main Methods:

  • Review of recent scientific literature.
  • Analysis of genetic approaches in yeast.
  • Exploration of drug-induced apoptosis in yeast.

Main Results:

  • Apoptosis features, including caspase-like activity, can be induced in yeasts.
  • DNA damage and other triggers can induce apoptosis in yeast.
  • Yeasts offer a model for studying DNA damage, cell cycle, and apoptosis.

Conclusions:

  • Yeasts are a powerful model for apoptosis research.
  • Further research in yeast can inform cancer therapeutic strategies.
  • Understanding yeast apoptosis can lead to novel drug development for cancer treatment.

Related Experiment Videos