Atrial myxoma as a cause of stroke: case report and discussion

Fintan O'Rourke1, Naeem Dean, Mikael S Mouradian

  • 1Stroke Prevention Clinic, University of Alberta Hospital, Edmonton, AB. forourke@ualberta.ca

Insights

Cardiac myxoma can cause serious embolic events like stroke if not diagnosed early. Prompt cardiac investigation is crucial for timely treatment and preventing severe outcomes.

Area of Science:

  • Cardiology
  • Neurology
  • Vascular Medicine

Background:

  • Cardiac myxoma is a rare primary tumor of the heart.
  • It can lead to embolic events affecting the central nervous system and other organs.
  • Diagnosis can be delayed due to nonspecific symptoms or lack of cardiac history.

Observation:

  • Nonspecific systemic symptoms and minor embolic phenomena may be overlooked.
  • Cardiac investigations are often not performed in the absence of known cardiac issues.
  • A case is presented where diagnosis was delayed until significant embolic disease, like stroke, occurred.

Findings:

  • Cardiac myxoma is a significant source of emboli.
  • Delayed diagnosis can lead to severe neurological deficits, such as functional impairment from stroke.
  • Early recognition of subtle signs is key.

Implications:

  • Highlights the importance of considering cardiac myxoma in patients with unexplained embolic events.
  • Emphasizes the need for cardiac investigations even with nonspecific symptoms.
  • Timely diagnosis and treatment can prevent devastating sequelae like stroke.

Related Concept Videos

Ischemic Stroke l: Introduction01:15

Ischemic Stroke l: Introduction

Ischemic stroke is an acute cerebrovascular condition in which blood flow to a brain region is suddenly interrupted, leading to tissue infarction. Neurons depend on continuous oxygen and glucose supply, so even brief reductions in perfusion cause energy failure, ionic imbalance, and irreversible injury. Ischemic strokes are classified into thrombotic and embolic types based on their underlying mechanisms.Thrombotic MechanismsThrombotic stroke develops when a clot forms within a cerebral artery.
Transient Ischemic Attack l: Introduction01:26

Transient Ischemic Attack l: Introduction

A transient ischemic attack (TIA) is a brief episode of neurological dysfunction caused by a temporary, focal reduction in cerebral blood flow. Although symptoms resemble those of an ischemic stroke, the interruption in perfusion is short-lived and does not cause permanent infarction. TIAs are clinically important because they often serve as early warning events for future stroke.Mechanisms of Transient Cerebral IschemiaTransient cerebral ischemia may arise through several mechanisms. One...
Hemorrhagic Stroke l: Introduction01:17

Hemorrhagic Stroke l: Introduction

A hemorrhagic stroke is an acute neurological event that occurs when a weakened cerebral blood vessel ruptures, allowing blood to accumulate within or around the brain. The sudden release of blood forms a focal hematoma that increases intracranial pressure, displaces neural tissue, and can obstruct cerebrospinal fluid pathways. These effects may be compounded by intraventricular extension of the hemorrhage, cerebral edema, or compression of adjacent structures, all of which contribute to...
Stroke: Introduction and Types01:29

Stroke: Introduction and Types

A stroke is an acute neurological event caused by the sudden disruption of cerebral blood flow, leading to rapid loss of neuronal function. Neurons depend on continuous oxygen and glucose supply, so even brief interruptions can cause irreversible injury within minutes. Strokes are classified into ischemic and hemorrhagic types.Ischemic StrokeIschemic strokes are most common and occur due to arterial occlusion, depriving brain tissue of oxygen and nutrients. This leads to energy failure, ionic...
Mitral Stenosis I: Introduction01:22

Mitral Stenosis I: Introduction

Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
Ischemic Stroke ll: Pathophysiology01:15

Ischemic Stroke ll: Pathophysiology

An ischemic stroke occurs when a cerebral blood vessel becomes obstructed, most often by a thrombus or embolus, interrupting the delivery of oxygen and glucose to brain tissue. Because neurons rely on continuous aerobic metabolism, energy failure begins within minutes of reduced perfusion. The region receiving the least blood flow becomes the infarct core, an area of irreversible cellular death. Surrounding this core lies the penumbra, a zone of hypoperfused but still viable tissue that is...