Related Experiment Videos

Group A streptococcal meningitis as a complication of an infected capillary haemangioma

Massoud Rezvani1, Jerome Y Yager, Dawn S Hartfield

  • 1Department of Paediatrics, Royal University Hospital, 103 Hospital Drive, S7N 0W8 Saskatoon, Saskatchewan, Canada.

Insights

Group A Streptococcus meningitis in an infant, caused by an infected capillary hemangioma, led to severe neurological issues. Aggressive treatment of infected hemangiomas is crucial for young children.

Area of Science:

  • Pediatric infectious diseases
  • Neonatal neurology
  • Dermatology

Background:

  • Capillary hemangiomas are benign vascular tumors that can become infected.
  • Group A Streptococcus (GAS) is a common bacterial pathogen.
  • Meningitis is a serious infection of the membranes surrounding the brain and spinal cord.

Observation:

  • A case report details an infant with meningitis caused by GAS originating from an infected capillary hemangioma.
  • The infant experienced severe complications, including cerebral infarction, epilepsy, and developmental delay.

Findings:

  • Group A Streptococcus can be a highly virulent pathogen in infants.
  • Infected capillary hemangiomas pose a significant risk for invasive GAS infections and subsequent neurological morbidity.

Implications:

  • Prompt and aggressive treatment of infected capillary hemangiomas is recommended to prevent severe outcomes.
  • Further research is needed to establish consistent treatment guidelines for infected capillary hemangiomas.
Abstract

Related Concept Videos

Bacterial Meningitis I: Introduction01:22

Bacterial Meningitis I: Introduction

Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...
Cryptococcal Meningitis01:27

Cryptococcal Meningitis

Cryptococcal meningitis is a life-threatening opportunistic infection predominantly associated with HIV/AIDS, accounting for over 100,000 deaths annually worldwide. However, it also affects individuals with other forms of immunosuppression, including those undergoing immunosuppressive therapy, organ transplant recipients, patients with innate immunodeficiencies, and individuals with hematological disorders. The infection is caused mainly by Cryptococcus neoformans and Cryptococcus gattii,...
Bacterial Meningitis01:24

Bacterial Meningitis

Bacterial meningitis is a severe infectious disease involving inflammation of the meninges, the protective membranes surrounding the brain and spinal cord. It occurs when pathogenic bacteria cross the blood–brain barrier and enter the cerebrospinal fluid. Common causative organisms include Neisseria meningitidis, Streptococcus pneumoniae, Haemophilus influenzae type b, Listeria monocytogenes, and Escherichia coli K1. The exact route of entry varies by pathogen and host condition.Routes of Entry...
Bacterial Meningitis II: Pathophysiology01:26

Bacterial Meningitis II: Pathophysiology

Bacterial meningitis typically begins when pathogens such as Neisseria meningitidis and Streptococcus pneumoniae colonize the nasopharynx and invade the bloodstream. This process is facilitated by bacterial virulence factors, such as polysaccharide capsules, which resist phagocytosis and complement-mediated killing. Less commonly, bacteria reach the central nervous system via contiguous spread from infections like otitis media or sinusitis, through congenital or acquired dural defects, or...
Brain Abscess l: Introduction01:26

Brain Abscess l: Introduction

A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial infections,...
Viral Meningitis01:18

Viral Meningitis

Viral meningitis is the most common form of meningitis and is often referred to as aseptic meningitis to indicate the absence of bacterial involvement. It is generally milder than bacterial meningitis, with symptoms including fever, headache, stiff neck, drowsiness, nausea, photophobia, and vomiting. Rarely, more severe manifestations or death may occur. Common causative agents include enteroviruses, particularly coxsackie A and B viruses and echoviruses, all members of the Enterovirus genus...