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Efficient and sequence-specific DNA-templated polymerization of peptide nucleic acid aldehydes

Daniel M Rosenbaum1, David R Liu

  • 1Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA.

Journal of the American Chemical Society
|November 13, 2003
PubMed
Summary

Researchers developed DNA-templated polymerizations for synthetic peptide nucleic acid (PNA) aldehydes. This efficient, sequence-specific method creates long PNA polymers, enabling the evolution of synthetic polymers.

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