[Oral lichen planus and liver pathology. II. The clinico-statistical correlations between oral manifestations and...

To characterize with more precision the association between oral lichen planus (OLP) and hepatopathies, 96 patients with OLP were separated in two groups ordered by presence or absence of liver diseases comparing some variables (age, sex, presence of pain, clinical variety, presence of skin lesions, alcohol consumption and exposure to drugs inducing hepatic injury) and evaluating the statistical significance. Factors associated with increased frequency of liver diseases were erosive variety of OLP (p = 0.024) and presence of pain (p = 0.026) (chi square test with Yates correction). It's confirmed that OLP patients with higher risk of liver disease are those that have erosive lesions with severe symptoms and often diffused in the entire oral cavity; furthermore, it's highlighted that the probability to find liver disease associated with reticular and plaque-like form of OLP is low, but not negligible.