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Updated: Jun 27, 2026

Electrophysiological Measurements and Analysis of Nociception in Human Infants
Published on: December 20, 2011
Current status of pain management in children
1Anaesthesia and Pain Management, Children Nationwide Pain Research Centre, and Department of Anaesthesia, Great Ormond Street Hospital for Children NHS Trust, London, England. r.howard@ich.ucl.ac.uk
Insights
Pediatric pain management has advanced, yet effective treatments aren't widely used. Early life pain can cause long-term issues, highlighting the need for more research in children's pain care.
Area of Science:
- Pediatric Pain Management
- Developmental Neuroscience
- Clinical Practice Advancement
Background:
- Significant progress in understanding pediatric pain and acute pain management has occurred.
- Despite advances, evidence-based pediatric pain management is not consistently applied in clinical practice.
- Early life pain experiences are increasingly recognized for their potential long-term consequences.
Purpose of the Study:
- To review the current state of pediatric pain management.
- To highlight the gap between research findings and clinical practice.
- To emphasize the long-term implications of early life pain and the need for further research.
Main Methods:
- Review of recent findings in laboratory and clinical studies on pediatric pain.
- Analysis of factors influencing long-term outcomes of infant pain.
- Assessment of the challenges in managing chronic and neuropathic pain in children.
Main Results:
- Knowledge regarding safe and effective pain management in children has increased.
- Research indicates early pain can lead to long-term behavioral changes beyond recovery.
- Chronic and neuropathic pain are more prevalent in children than previously assumed.
Conclusions:
- There is a critical need to translate existing knowledge into routine pediatric pain care.
- Further research is essential to understand and manage the long-term effects of early pain.
- Improved strategies for assessing and treating chronic pain in children are urgently required.
Abstract:
Many changes have taken place in pediatric pain management since the undertreatment of children's pain was first reported. Notable advances include an increase in understanding pain during development and improvements in the management of acute pain. Although much more about the safe and effective management of pain in children is now known, this knowledge has not been widely or effectively translated into routine clinical practice. Lack of suitable research on which to firmly establish evidence-based care is likely to have contributed to this situation. A subject of considerable interest recently is the discovery that the experience of pain in early life may lead to long-term consequences. New research findings from laboratory and clinical studies have clearly identified possible mechanisms and provided evidence that long-term behavioral changes can extend far beyond what would be considered the normal period of postinjury recovery. Timing, degree of injury, and administered analgesia and its nature may be important determinants of the long-term outcome of infant pain. Chronic pain, including neuropathic pain, is far more common in children than was thought. The assessment and treatment of this pain and its functional consequences present a considerable unmet challenge. There is a pressing need for further research and clinical development in the management of pain in children.
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