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Current medical abortion care.

Mitchell D Creinin¹

¹University of Pittsburgh, Magee-Womens Hospital, 300 Halket Street, Pittsburgh, PA 15213-3180, USA. mcreinin@mail.magee.edu

Current Women'S Health Reports

|November 14, 2003

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Medical abortion with mifepristone and misoprostol is a safe and effective early abortion method. The standard regimen of 200 mg mifepristone followed by 800 mcg vaginal misoprostol achieves over 95% complete abortion rates.

Area of Science:

Reproductive Health
Pharmacology

Background:

Medical abortion using mifepristone and a prostaglandin analogue offers a safe alternative to surgical abortion.
Since 1988, mifepristone has enabled millions of women to access safe abortion care.
Regimens for medical abortion have been refined to reduce costs and time to abortion.

Purpose of the Study:

To review the evolution and current standard of care for medical abortion.
To highlight the efficacy and acceptability of mifepristone-misoprostol regimens.

Main Methods:

Review of clinical studies and established medical abortion protocols.
Focus on the widely adopted mifepristone-misoprostol regimen.

Main Results:

Mifepristone 200 mg followed by 800 mcg vaginal misoprostol at least 24 hours later is a highly effective regimen.

Related Experiment Videos

Complete abortion rates exceed 95% with this method.

Self-administration of misoprostol is feasible and effective.

Conclusions:

Medical abortion with mifepristone and misoprostol is a highly effective and safe option for early pregnancy termination.
Ongoing research aims to further improve medical abortion outcomes and patient acceptability.