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Related Experiment Videos

Lymphosarcoma in a brown bear (Ursus arctos).

B I Yoon1, J K Lee, J H Kim

  • 1Division of Cellullar and Molecular Pathogenesis, Department of Pathology, Virginia Commonwealth University, Richimond, Virginia 23298-0297, USA.

Journal of Veterinary Science
|November 14, 2003
PubMed
Summary

A lymphoblastic lymphosarcoma, a type of cancer, was diagnosed in a brown bear (Ursus arctos). This marks the first reported case in Korea, highlighting a rare occurrence in the Ursidae family.

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Area of Science:

  • Veterinary Pathology
  • Comparative Oncology
  • Wildlife Disease

Background:

  • Lymphosarcoma is a malignant tumor of lymphocytes, commonly affecting various animal species.
  • Brown bears (Ursus arctos) are large omnivorous mammals found across the Northern Hemisphere.
  • Understanding cancer prevalence in wildlife is crucial for conservation and public health.

Observation:

  • A 7-year-old male brown bear presented with a 7-month history of depression, anorexia, and watery diarrhea.
  • Post-mortem examination revealed enlarged mesenteric lymph nodes (4-6 times normal size).
  • Histological analysis confirmed lymphoblastic lymphosarcoma with small intestinal mucosal thickening and hepatic metastasis.

Findings:

  • The bear was diagnosed with lymphoblastic lymphosarcoma, a rare cancer in Ursidae.

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  • Grossly, mesenteric lymph nodes were significantly enlarged.
  • Microscopic examination showed neoplastic cell infiltration in the small intestine and liver metastasis.
  • Endogenous lipid pneumonia was an incidental finding in the lungs.

    • Implications:

    • This case represents the first documented instance of lymphosarcoma in the Ursidae family in Korea.
    • Highlights the importance of considering neoplastic diseases in free-ranging wildlife.
    • Contributes to the understanding of cancer biology in non-domesticated mammals.