Outbreak of severe rotavirus gastroenteritis among children--Jamaica, 2003

    Insights

    Jamaica experienced a significant rise in acute gastroenteritis (AGE) cases and deaths among young children in 2003. Rotavirus was identified as the cause, with better case management potentially reducing fatalities.

    Area of Science:

    • Public Health
    • Infectious Diseases
    • Pediatrics

    Background:

    • A sharp increase in acute gastroenteritis (AGE) cases, hospital admissions, and deaths among children was observed in Jamaica in May 2003.
    • The Kingston and St. Andrew parish reported the highest incidence of AGE among children under 5 years old.
    • Twelve AGE-associated deaths in children under 8 years old were reported during June-July.

    Purpose of the Study:

    • To investigate the etiology of the acute gastroenteritis outbreak in Jamaica.
    • To identify risk factors associated with AGE illness and mortality.
    • To recommend appropriate control measures for the outbreak.

    Main Methods:

    • The Jamaican Ministry of Health initiated an epidemiological investigation.
    • Data collection focused on case identification, risk factor analysis, and mortality assessment.
    • Preliminary findings were compiled to understand the outbreak's dynamics.

    Main Results:

    • The acute gastroenteritis outbreak was strongly associated with rotavirus infection.
    • Deaths related to AGE may have been preventable with adequate case management.
    • A need for enhanced caregiver education on AGE treatment was identified.

    Conclusions:

    • Rotavirus was the primary cause of the acute gastroenteritis outbreak in Jamaica.
    • Improved case management and caregiver education are crucial for reducing pediatric mortality from AGE.
    • Public health interventions should focus on rotavirus prevention and effective AGE treatment strategies.

    Related Concept Videos

    Bacterial Gastroenteritis01:18

    Bacterial Gastroenteritis

    Bacterial gastroenteritis, characterized by diarrhea, abdominal cramps, and vomiting, is often caused by ingestion of contaminated food or water and is frequently associated with pathogenic Escherichia coli strains. These microbes exploit two principal mechanisms to inflict disease.Shiga toxin–producing E. coli, also referred to as STEC—notably O157:H7—release Shiga toxins that target ribosomes, blocking protein synthesis. The B subunit of the toxin binds the host glycolipid receptor...
    Investigation of Disease Outbreaks01:23

    Investigation of Disease Outbreaks

    Multistate foodborne outbreaks pose significant public health risks and require meticulous investigation to identify sources and implement control measures. The Centers for Disease Control and Prevention (CDC) utilizes a dynamic seven-step process for these investigations, integrating data from laboratories, interviews, and environmental assessments to protect public health.Outbreak Detection: The detection of multistate outbreaks typically begins with PulseNet, the CDC's national laboratory...
    Cholera01:25

    Cholera

    Cholera is an acute gastrointestinal disease caused by the Gram-negative bacterium Vibrio cholerae. It is transmitted primarily via the fecal-oral route through the ingestion of contaminated water or food.Vibrio cholerae is a motile, Gram-negative bacterium of the family Vibrionaceae, primarily associated with waterborne outbreaks in areas with inadequate sanitation. Although over 200 serogroups of V. cholerae exist, only O1 and O139 are responsible for epidemic cholera. The O1 serogroup,...
    Respiratory Syncytial Virus Disease01:29

    Respiratory Syncytial Virus Disease

    Human respiratory syncytial virus (RSV) is a widespread pathogen that primarily targets infants and young children but also poses a serious health risk to elderly and immunocompromised individuals. Belonging to the Pneumoviridae family, RSV is a negative-sense, single-stranded RNA virus within the Pneumovirus genus. Its global health burden is significant, with millions of cases annually resulting in hospitalizations and mortality, particularly in resource-limited settings. Although most...
    Botulism01:22

    Botulism

    Botulism is a life-threatening neuroparalytic condition caused by botulinum neurotoxin, which is produced by the bacterium Clostridium botulinum, a Gram-positive, spore-forming, obligate anaerobe.In adults, the toxin enters the body in different ways: in foodborne botulism, the preformed toxin is absorbed in the intestine. In wound botulism, spores grow in injured tissue and release the toxin into the blood. Infant botulism differs mechanistically from adult forms. In infants, botulism commonly...
    Diphtheria01:28

    Diphtheria

    Diphtheria is an acute, toxin-mediated infectious disease that primarily affects the upper respiratory tract. It is caused by Corynebacterium diphtheriae, a Gram-positive, pleomorphic rod that lacks spore-forming capability and exhibits a characteristic club-shaped morphology under microscopic examination. While C. diphtheriae can asymptomatically colonize mucosal surfaces, clinical disease manifests only when the bacterial strain is lysogenized by a specific β-corynephage. This phage...