Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Migraine: an ophthalmologist's perspective.

Guruswami Arunagiri1, Shanmugam Santhi

  • 1Neuro-Ophthalmology Service, Department of Ophthalmology, Geisinger Medical Center, Danville, Pennsylvania 17822, USA. eye@usa.com

Current Opinion in Ophthalmology
|November 15, 2003
PubMed
Summary

Recent advances in functional neuroimaging reveal that brainstem structures initiate migraine attacks, preceding occipital cortex activation. Cortical spreading depression activates the trigeminovascular system, leading to headache. Genetic loci for migraine have also been identified.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Intravitreal bevacizumab for the treatment of choroidal neovascularization secondary to pseudotumor cerebri.

International ophthalmology·2008
Same author

Horner syndrome and ipsilateral abduction deficit attributed to giant cell arteritis.

Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society·2006
See all related articles

Area of Science:

  • Neurology
  • Ophthalmology
  • Genetics

Background:

  • Migraine is a common neurological disorder often presenting with visual symptoms.
  • Ophthalmologists frequently encounter patients with undiagnosed migraine, necessitating their understanding of the condition.
  • Neurologic syndromes involving migraine and retinopathy require ophthalmologic expertise for diagnosis.

Purpose of the Study:

  • To review the evolving understanding of migraine, focusing on ocular manifestations.
  • To highlight recent advancements in migraine pathogenesis and genetics.
  • To emphasize the ophthalmologist's role in diagnosing and managing migraine patients.

Main Methods:

  • Review of recent scientific literature on migraine.
  • Analysis of functional neuroimaging studies (fMRI).

Related Experiment Videos

  • Discussion of genetic studies identifying migraine loci.

    • Main Results:

    • Functional neuroimaging suggests brainstem structures initiate migraine attacks, preceding occipital cortex activation.
    • Cortical spreading depression activates the trigeminovascular system, a key event in migraine headache.
    • New genetic loci for migraine with and without aura have been identified on chromosomes 6, 14, and 4.

    Conclusions:

    • Migraine understanding is rapidly advancing due to functional neuroimaging.
    • Ophthalmologists play a crucial role in identifying and managing patients with migraine.
    • Further research is needed to address unanswered questions in migraine epidemiology, genetics, and management.