Related Experiment Video

Updated: Aug 5, 2026

Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring
17:16

Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring

Published on: December 9, 2010

Conventional and diffusion-weighted MRI in the evaluation of methanol poisoning

A Server1, K E Hovda, P Hj Nakstad

  • 1Departments of Neuroradiology, Division of Radiology, and Medicine, Ullevål University Hospital, Oslo, Norway. Andres.ServerAllonso@ulleval.no

Acta Radiologica (Stockholm, Sweden : 1987)
|November 18, 2003
PubMed

Insights

Methanol poisoning can cause cerebral lesions, particularly in the putamina. Magnetic resonance imaging (MRI) revealed cytotoxic edema and post-necrotic changes in two patients, highlighting the neurotoxic effects of methanol.

Area of Science:

  • Neurology
  • Radiology
  • Toxicology

Background:

  • Methanol poisoning is a serious condition that can lead to severe neurological deficits.
  • Magnetic resonance imaging (MRI) is a crucial tool for diagnosing and understanding the extent of brain damage.

Observation:

  • Two cases of methanol poisoning were examined using conventional MRI.
  • Diffusion-weighted MRI (DWI) and fluid-attenuated inversion recovery (FLAIR) sequences were utilized.

Findings:

  • Conventional MRI revealed symmetrical, bilateral increased signals in the lentiform nuclei (predominantly putamina) extending to surrounding white matter in one patient.
  • Diffusion-weighted MRI (DWI) indicated decreased diffusion in these areas, suggesting cytotoxic edema.
  • The second patient exhibited putaminal hyperintensity on FLAIR and T2-weighted images, indicative of post-necrotic changes.

Implications:

  • These findings underscore the characteristic neuroimaging patterns of methanol-induced brain injury.
  • MRI, including DWI, is valuable for early detection and characterization of cerebral lesions in methanol poisoning.
  • Understanding these patterns aids in clinical management and prognosis assessment for methanol-exposed individuals.

More Related Videos

Simultaneous PET/MRI Imaging During Mouse Cerebral Hypoxia-ischemia10:35

Simultaneous PET/MRI Imaging During Mouse Cerebral Hypoxia-ischemia

Published on: September 20, 2015

Advanced Diffusion Imaging in The Hippocampus of Rats with Mild Traumatic Brain Injury10:33

Advanced Diffusion Imaging in The Hippocampus of Rats with Mild Traumatic Brain Injury

Published on: August 14, 2019

Related Concept Videos

Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
Imaging Studies for Cardiovascular System IV: CMRI01:21

Imaging Studies for Cardiovascular System IV: CMRI

Cardiovascular magnetic resonance imaging, or CMRI, is a non-invasive diagnostic test that employs a magnetic field and radiofrequency waves to create precise images of the heart and arteries. It provides comprehensive information about cardiac anatomy, function, perfusion, and tissue characterization without ionizing radiation.IndicationsCMRI diagnoses various heart conditions, including tissue damage from heart attacks, ischemic heart disease, myocarditis, aortic issues (tears, aneurysms,...