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A Controlled Mouse Model for Neonatal Polymicrobial Sepsis
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A Controlled Mouse Model for Neonatal Polymicrobial Sepsis

Published on: January 27, 2019

Salmonella sepsis and miscarriage

L B Coughlin1, J McGuigan, N G Haddad

  • 1Department of Obstetrics and Gynecology, Whiston Hospital, Warrington Lane, Prescot, Merseyside, L35 5DR, UK. drlbc@aol.com

Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases
|November 18, 2003
PubMed

We present a case of a miscarriage at 16 weeks of gestation due to infection and transplacental passage of Salmonella group C. This was identified as being Salmonella Virchow from genital tract swab culture, and placental Gram-staining revealed numerous colonies of Gram-negative bacilli within the fibrin between the placental villi, confirming a true villitis associated with a hematogenous infection. Based on the patient's history, it was suggested that she had contracted the salmonella infection from eating undercooked eggs. Treatment of salmonella infection in pregnancy is controversial, and antibiotic therapy should be reserved for cases of invasive disease, using amoxicillin or a cephalosporin.

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