Related Experiment Video
Updated: Aug 14, 2026

10:30
Multi-exon Skipping Using Cocktail Antisense Oligonucleotides in the Canine X-linked Muscular Dystrophy
Published on: May 24, 2016
Robertsonian translocation (8;14) in an infertile bitch (Canis familiaris)
Marek Switonski1, Izabela Szczerbal, Anna Skorczyk
1Department of Genetics and Animal Breeding, August Cieszkowski Agricultural University of Poznań, Poland. switonsk@jay.au.poznan.pl
Journal of Applied Genetics
|November 18, 2003
Abstract:
A new case of a Robertsonian translocation diagnosed in an infertile bitch of West Highland White Terrier breed is reported. Cytogenetic analyses were performed with the use of Giemsa staining, Q-, C- and Ag-I banding techniques and FISH with canine whole X chromosome paint. The karyotype of this bitch was described as 77,XX der (8;14)(q10;q10).
Related Concept Videos
Multiple Allele Traits
The Concept of Multiple Allelism
Sex-linked Disorders
Like autosomes, sex chromosomes contain a variety of genes necessary for normal body function. When a mutation in one of these genes results in biological deficits, the disorder is considered sex-linked.
Nondisjunction
During meiosis, chromosomes occasionally separate improperly. This occurs due to failure of homologous chromosome separation during meiosis I or failed sister chromatid separation during meiosis II. In some species, notably plants, nondisjunction can result in an organism with an entire additional set of chromosomes, which is called polyploidy. In humans, nondisjunction can occur during male or female gametogenesis and the resulting gametes possess one too many or one too few chromosomes.

