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[Production technology and analysis of blood circulation improving tincture]
Jurga Bernatoniene1, Rūta Bernatoniene, Valdas Jakstas
1Faculty of Pharmacy, Kaunas University of Medicine, Kaunas, Lithuania.
Abstract:
This article deals with the production of the tincture of Ginkgo biloba leaves, Crataegus fruits and Leonurus herbs while selecting an extractant, the size of particles in a raw material and possible methods of extraction. The optimal composition of ethanol 70%, the particle size of Ginkgo biloba leaves and Crataegus fruits 2-3 mm of Leonurus herbs. The method of production--percolation, the flow speed 0.5 ml/min. The tincture was analyzed at determination of the sum of flavonoids in terms of quercetin, dry residue, relative density, ethanol concentration. The quality of the tincture was evaluated by high-pressure liquid chromatography and spectrophotometry. The stability of the tincture and its expiry date were fixed.