Related Experiment Video

Updated: Aug 30, 2026

Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information
09:37

Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information

Published on: August 15, 2019

[Tietze's syndrome in a 2-year old boy]

J M Pijning1, H de Boeck, B Desprechins

  • 1Afd. Kindergeneeskunde, Academisch Ziekenhuis Kinderen van de Vrije Universiteit Brussel, België. j.m.pijning@amc.uva.nl

Nederlands Tijdschrift Voor Geneeskunde
|November 19, 2003
PubMed

Insights

Tietze's syndrome, a painful chest swelling, can affect children and typically resolves on its own. Early recognition prevents unnecessary medical interventions for this benign condition.

Area of Science:

  • Pediatric Rheumatology
  • Medical Imaging

Background:

  • Tietze's syndrome is a rare, benign inflammatory condition causing localized swelling of costosternal or costochondral joints.
  • While typically seen in adults, it can occur in children, presenting diagnostic challenges.

Observation:

  • A 2-year-old boy presented with painful swelling of the left costochondral junction.
  • Imaging revealed swelling in the 4th and 5th costochondral junctions and pectoral muscle, with no signs of infection.
  • A conservative, 'wait-and-see' approach was adopted due to suspected Tietze's syndrome.

Findings:

  • Symptoms gradually subsided over a 10-week period.
  • Final examination showed only slight, painless swelling with normal ultrasound findings.
  • The case illustrates the characteristic spontaneous regression of Tietze's syndrome.

Implications:

  • Accurate diagnosis of Tietze's syndrome in children is crucial to avoid invasive procedures.
  • Understanding the benign and self-limiting nature of this condition aids clinical management.
  • Knowledge of Tietze's syndrome outcomes can improve patient care and reduce healthcare costs.

More Related Videos

In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila06:41

In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila

Published on: August 20, 2019

Behavioral Assessment of Hearing in 2 to 4 Year-old Children: A Two-interval, Observer-based Procedure Using Conditioned Play-based Responses14:05

Behavioral Assessment of Hearing in 2 to 4 Year-old Children: A Two-interval, Observer-based Procedure Using Conditioned Play-based Responses

Published on: January 23, 2017

Related Concept Videos

Mitral Stenosis II: Clinical features and Diagnostic Tests01:23

Mitral Stenosis II: Clinical features and Diagnostic Tests

Mitral stenosis is a heart condition in which the mitral valve, which allows blood to flow from the left atrium to the left ventricle, becomes narrowed or stenotic. This narrowing hinders blood flow and leads to clinical symptoms requiring specific medical evaluations and management strategies. The following overview outlines the clinical symptoms, assessments, diagnostic findings, prevention methods, and treatments for mitral stenosis.Clinical ManifestationsDyspnea (shortness of breath): This...
Intestinal Obstruction II: Pathophysiology01:07

Intestinal Obstruction II: Pathophysiology

Intestinal obstruction triggers a series of physiological responses, starting with gas and fluid accumulation in the bowel segment proximal to the obstruction, leading to distension. This distended intestine compresses the diaphragm, hindering lung expansion and potentially leading to reduced respiratory effort, atelectasis, and pneumonia.To overcome the blockage, the gut intensifies contractions, causing colicky abdominal pain, nausea, and vomiting, which reduces fluid and food intake and...
Sex-linked Disorders02:28

Sex-linked Disorders

Like autosomes, sex chromosomes contain a variety of genes necessary for normal body function. When a mutation in one of these genes results in biological deficits, the disorder is considered sex-linked.Y chromosome mutations are called “Y-linked” and only affect males since they alone carry a copy of that chromosome. Mutations to the relatively small Y chromosome can impact male sexual function and secondary sex characteristics. Y-chromosome infertility is a disorder that affects sperm...
Pedigree Analysis02:21

Pedigree Analysis

A pedigree is a diagram displaying a family’s history of a trait. Analyzing pedigrees can reveal (1) whether a trait is dominant or recessive, (2) the type of chromosome, autosomal or sex, a trait is linked to, (3) genotypes of family members, and (4) probabilities of phenotypes in future generations. For families with a history of autosomal or sex-linked diseases, this information can be crucial to family planning.Pedigrees Display Family HistoriesIn various plant and animal species,...
Pleiotropy01:47

Pleiotropy

Pleiotropy is the phenomenon in which a single gene impacts multiple, seemingly unrelated phenotypic traits. For example, defects in the SOX10 gene cause Waardenburg Syndrome Type 4, or WS4, which can cause defects in pigmentation, hearing impairments, and an absence of intestinal contractions necessary for elimination. This diversity of phenotypes results from the expression pattern of SOX10 in early embryonic and fetal development. SOX10 is found in neural crest cells that form melanocytes,...