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Updated: Aug 11, 2026

A General Method for Detecting Nitrosamide Formation in the In Vitro Metabolism of Nitrosamines by Cytochrome P450s
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A General Method for Detecting Nitrosamide Formation in the In Vitro Metabolism of Nitrosamines by Cytochrome P450s

Published on: September 25, 2017

Molecular effects of nitrosamine toxicity

R L Bartzatt1, D L Nagel

  • 1Eppley Institute, University of Nebraska Center, Omaha 68198.

Physiological Chemistry and Physics and Medical NMR
|January 1, 1992
PubMed
Summary

Activated nitrosamines are highly reactive, readily alkylating various organic substrates. This reactivity suggests significant potential for in vivo toxicity, warranting further study of their reaction kinetics.

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