Related Experiment Video
Updated: Aug 10, 2026

A Package of Established Analytical Tools to Investigate the Solid-State Alteration of Lipid-Based Excipients
Published on: August 9, 2022
[The excipient properties of shea butter compared with vaseline and lanolin]
Oumar Thioune1, Barham Khouma, Mounibé Diarra
1Laboratoire de Pharmacie Galénique et Législation, Faculté de Médecine, de Pharmacie et d'Odonto-stomatologie-UCAD, Dakar, Sénégal.
Abstract:
A shea butter ointment containing 3% aureomycin (clortetracyclin hydrocloride) was prepared and some of its macroscopic and microscopic characteristics were evaluated. Then, the release of the active ingredient was compared by UV spectrophotometry with those obtained when excipients such as petroleum jelly and lanoline were used. Results had shown that the shea butter ointment had satisfactory characteristics. In the other hand, it was found that shea butter released the aureomycin easily and at a faster rate than the other excipients.
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