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Related Experiment Videos

Intestinal transplantation.

Olivier Goulet1, Yann Révillon

  • 1Combined Programme of Intestinal Transplantation Hôspital Necker-Enfants Malades, Paris, France. olivier.goulet@nck.ap-hop-paris.fr

Indian Journal of Pediatrics
|November 19, 2003
PubMed
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Intestinal transplantation (ITx) is now a standard treatment for permanent intestinal failure, offering an acceptable clinical option for select patients. Further research is needed on graft function and monitoring post-transplant.

Area of Science:

  • Gastroenterology and Hepatology
  • Transplant Surgery
  • Immunology

Background:

  • Intestinal transplantation (ITx) has evolved due to improved immunosuppression and acute rejection management.
  • Permanent intestinal failure necessitates alternative treatment options.
  • ITx is increasingly recognized as a viable clinical modality.

Purpose of the Study:

  • To review the indications for intestinal transplantation.
  • To summarize the clinical outcomes and results of ITx.
  • To discuss the complications associated with ITx.

Main Methods:

  • Review of data from the Intestinal Transplant International Registry.
  • Analysis of clinical outcomes and complications reported in the literature.
  • Synthesis of current knowledge on ITx indications and results.

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Main Results:

  • ITx is an acceptable treatment for selected patients with permanent intestinal failure.
  • The Intestinal Transplant International Registry provides key data on ITx outcomes.
  • Significant advancements in immunosuppression and rejection control have improved ITx success.

Conclusions:

  • Intestinal transplantation is a standard treatment for permanent intestinal failure.
  • Further investigation into graft function and monitoring is crucial.
  • ITx offers a life-saving option for patients with irreversible intestinal failure.