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Updated: Aug 30, 2026

Multiplexed Fluorescent Immunohistochemical Staining, Imaging, and Analysis in Histological Samples of Lymphoma
Published on: January 9, 2019
Clinical, haematological, immunohistochemical and pathological findings in 10 cattle with cutaneous lymphoma
G Schweizer1, M Hilbe, U Braun
1Department of Veterinary Internal Medicine, University of Zurich, Winterthurerstrasse 260, CH-8057 Zurich, Switzerland.
Abstract:
This paper describes the clinical, haematological, immunohistochemical and pathological findings in 10 female cattle with cutaneous lymphoma. The most striking clinical finding was multifocal intracutaneous nodules, which were firm, hairless and sometimes covered with haemorrhagic crusts. All the animals had multiple lymphadenopathy. Eight of the animals had leucocytosis and two also had lymphocytosis. In seven animals, a definitive diagnosis of lymphosarcoma was made on the basis of biopsies of intracutaneous nodules or fine needle aspirates of superficial lymph nodes. In some of the cattle the kidneys, heart, spleen and lungs were affected.

