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Cultivation Methods of Spirochetes from Borrelia burgdorferi Sensu Lato Complex and Relapsing Fever Borrelia
Published on: November 25, 2022
Q fever outbreak during the Czech Army deployment in Bosnia
Miroslav Splino1, Jiri Beran, Roman Chlíbek
1Department of Epidemiology, Purkyne Military Medical Academy, Trebesska 1575, 500 01 Hradec Kralove, Czech Republic.
Abstract:
An epidemic of Q fever was identified among soldiers from the Czech Republic serving in the U.N. Stabilization Force in Bosnia and Herzogovina in 1997. There were 26 serologically confirmed infections, or 4.6% of those exposed. There were 14 cases of febrile illness and 12 subclinical infections. Prodromal symptoms of malaise, headache, backache, and fatigue were followed by fever > or = 39 degrees C with an intermittent course. Physical findings were unremarkable except in five cases with radiographically confirmed pneumonia. Cases were treated with doxycycline, trimethoprim-sulfamethoxazole, or ceftriaxone and supportive care. Q fever occurred at four U.N. Stabilization Force bases with the highest incidence at Dolna Ljubija (attack rate 9.4% vs. 2.3% at other locations (risk ratio = 4.0; 95% confidence interval [CI] = 2.7-5.9; p < 0.05). A sheep farm with active lambing was located 100 m from the base. Helicopter operations at a nearby landing zone may have generated infectious environmental aerosols and may have been a cause of the Q fever outbreak.
Insights
An outbreak of Q fever affected Czech soldiers in Bosnia in 1997, with 4.6% infected. Proximity to a sheep farm and helicopter activity near a military base were potential causes.
Area of Science:
- Epidemiology
- Infectious Diseases
- Military Medicine
Background:
- Q fever is a zoonotic disease caused by Coxiella burnetii.
- Military deployments can increase exposure to novel infectious agents.
- Outbreaks in deployed forces require rapid identification and control.
Purpose of the Study:
- To investigate an epidemic of Q fever among United Nations (U.N.) Stabilization Force soldiers in Bosnia and Herzegovina in 1997.
- To identify risk factors and potential sources of infection.
- To describe clinical presentation and treatment outcomes.
Main Methods:
- Serological confirmation of Q fever infections in soldiers.
- Retrospective analysis of case data, including symptoms and clinical findings.
- Epidemiological investigation to identify potential environmental exposures and transmission routes.
Main Results:
- Twenty-six soldiers (4.6%) had confirmed Q fever infections, with 14 experiencing febrile illness and 12 subclinical infections.
- Pneumonia was observed in five cases.
- The highest incidence occurred at Dolna Ljubija base (9.4% attack rate), near a sheep farm and helicopter operations.
Conclusions:
- The Q fever outbreak was linked to environmental exposure, likely from a nearby sheep farm.
- Helicopter operations may have aerosolized infectious agents, contributing to the outbreak.
- Prompt diagnosis and treatment with antibiotics like doxycycline are crucial for managing Q fever in deployed personnel.
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