Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Creatine supplementation and athletic performance.

Susan B Racette¹

¹Washington University School of Medicine, Program in Physical Therapy, Department of Medicine, St. Louis, MO 63108-2212, USA. racettes@msnotes.wustl.edu

The Journal of Orthopaedic and Sports Physical Therapy

|November 19, 2003

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Metabolic Adaptations to Caloric Restriction: Time- and Group-Dependent Metabolomic Signatures from the CALERIE<sup>™</sup> Trial.

Research square·2026

Same author

Time-restricted eating in Alzheimer's disease (TREAD): A call for research.

Journal of Alzheimer's disease : JAD·2026

Same author

Quadriceps mitochondrial DNA quantity, quality, and gene expression after 2 years of calorie restriction: exploratory results from the CALERIE trial.

GeroScience·2026

Same author

Use of Machine Learning to Identify Determinants of Habitual-Preformed Water Intake.

The Journal of nutrition·2026

Same author

Effect of 2-Year Caloric Restriction in the Absence of Malnutrition on Indicators of Anemia, Iron Status, and Hepcidin in Healthy Adults: A Randomized Clinical Trial.

The Journal of nutrition·2026

Same author

Lifestyle strategies and mechanistic implications for slowing neurodegeneration.

npj metabolic health and disease·2026

Same journal

Perplexing Pubic Pain: How Clinicians Might Approach Assessing and Managing Pubic-Related Groin Pain in Athletes.

The Journal of orthopaedic and sports physical therapy·2026

Same journal

Prevalence of Symphyseal Radiographic Findings and Skeletal Maturity and Their Relationship With Groin Symptoms in PROfessional FEmale Football Players: A Multicenter Cohort Study.

The Journal of orthopaedic and sports physical therapy·2026

Same journal

Rehabilitation of Long-Standing Groin Pain in Athletes: A Scoping Review of Exercise Content and Reporting.

The Journal of orthopaedic and sports physical therapy·2026

Same journal

Could Hip Dysplasia Be the Problem?

The Journal of orthopaedic and sports physical therapy·2026

Same journal

Understanding Adult Hip Dysplasia: Clinical Presentation, Assessment Techniques, and Exercise-Driven Management Strategies.

The Journal of orthopaedic and sports physical therapy·2026

Same journal

Hip Muscle Strength Is Associated With Symptom Severity in People With Femoroacetabular Impingement Syndrome, but Only in Those With Preexisting Hip Muscle Weakness: A Secondary Analysis of Baseline Data From a Randomized Controlled Trial.

The Journal of orthopaedic and sports physical therapy·2026

See all related articles

Creatine monohydrate supplementation can enhance athletic performance and muscle mass in athletes. However, young athletes should exercise caution due to unknown long-term effects on growth and development.

Area of Science:

Sports Science
Nutritional Biochemistry

Background:

Ergogenic aids, including nutritional supplements, are widely used by athletes to improve performance.
Creatine monohydrate is a popular supplement known for its potential benefits and perceived safety.

Purpose of the Study:

To review the effects of creatine monohydrate supplementation on athletic performance and body composition.
To address the safety concerns and knowledge gaps regarding creatine use, particularly in young athletes.

Main Methods:

Review of existing scientific literature on creatine monohydrate supplementation.
Analysis of studies investigating creatine's impact on muscle creatine concentrations, lean body mass, strength, power, and exercise performance.

Main Results:

Related Experiment Videos

Oral creatine supplementation increases skeletal muscle creatine levels.
It promotes lean body mass gains with resistance training, enhances power and strength, and improves performance in intense, repeated exercise bouts.
Long-term safety and effects on growth and development in young athletes remain largely undetermined.

Conclusions:

Creatine monohydrate is a potentially beneficial and generally safe supplement for many athletes.
Further research is needed to establish the long-term safety and efficacy of chronic creatine supplementation, especially for adolescent athletes.
Ongoing clinical investigations will guide the appropriate use of creatine for athletes of all ages.