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Updated: Aug 30, 2026

Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging
Published on: March 14, 2025
Obsessive-compulsive disorder: unearthing a hidden problem
Samar El-Sayegh1, Scott Bea, Angela Agelopoulos
1Department of Psychiatry and Psychology, The Cleveland Clinic, The Cleveland Clinic Foundation, OH 44195, USA.
Abstract:
Obsessive-compulsive disorder (OCD) is the fourth most common psychiatric disorder. Yet patients often avoid seeking help because they are ashamed. Diagnosis is difficult, but familiarity with the nature of OCD and its current management helps primary care physicians identify patients with OCD and make informed judgments about treatment and referral. We review common symptoms, causes, drug therapy, behavioral therapy, and quality of life issues in patients with OCD.
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