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Updated: Aug 15, 2026

Distinctive Capillary Action by Micro-channels in Bone-like Templates can Enhance Recruitment of Cells for Restoration of Large Bony Defect
Published on: September 11, 2015
New frontiers in bone tissue engineering
Jay W Calvert1, Lee E Weiss, Michael J Sundine
1University of California, Irvine, Aesthetic and Plastic Surgery Institute, 200 Manchester Avenue, Suite 650, Orange, CA 92868, USA. jcalvert@uci.edu
Abstract:
No single scientific field can generate the ideal method of engineering bone. However, through collaboration and expansion of programs in bone tissue engineering, the right combination of materials, cells, growth factors, and methodology will come together for each clinical situation such that harvesting bone grafts will become obsolete. This article reviews the need for engineered bone and provides a historical perspective of bone engineering research, current research efforts, and the future direction of this work.
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