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[Chronobiological approach to renal colic]
F Bilora1, G Vettore, R Manfredini
1Ospedale Civile, Università di Padova.
Archivio Italiano Di Urologia, Nefrologia, Andrologia : Organo Ufficiale Dell'Associazione Per La Ricerca in Urologia = Urological, Nephrological, and Andrological Sciences
|December 1, 1992
Summary
Urinary tract colic pain exhibits a daily rhythm, with symptoms peaking at certain times. This chronobiological pattern was observed across all patient groups, regardless of age or sex.
Area of Science:
- Urology
- Chronobiology
- Nephrology
Context:
- Urinary tract calculosis, or kidney stones, can cause severe pain.
- Lithogenic and antilithogenic substances in urine show circadian fluctuations.
- Understanding pain rhythms can aid in patient management.
Purpose:
- To investigate the chronobiological rhythm of colic pain in patients with urinary tract calculosis.
- To determine if pain occurrence follows a circadian pattern.
- To analyze potential seasonal variations in pain incidence.
Summary:
- A chronobiological analysis using the Halberg single cosinor test was performed on 447 patients with urinary tract colic pain.
- Results confirmed a significant circadian rhythmicity in the occurrence of colic pain.
- No circannual variability was detected, possibly due to the study's geographic location.
Impact:
- The findings demonstrate a predictable daily pattern in urinary tract colic pain.
- This chronobiological insight may inform the timing of interventions and patient care.
- Further research could explore the mechanisms behind this circadian rhythm.