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Cervical lymphadenitis caused by Candida albicans.
1Department of Dermatology, Jinling Hospital, Medical College of Nanjing University, Nanjing, China. zwqhzsl@jlonline.com
Mycoses
|November 19, 2003
Summary
Candida albicans caused cervical lymphadenitis in a child, presenting as localized fungal invasion. Treatment with fluconazole was successful, indicating its efficacy for this rare presentation.
Area of Science:
- Mycology
- Immunology
- Pediatrics
Background:
- Cervical lymphadenitis is typically bacterial, making fungal causes rare.
- Candida albicans is an opportunistic pathogen, usually causing mucocutaneous or systemic infections.
Observation:
- An 8-year-old Chinese child presented with cervical lymphadenitis.
- The infection was localized to a lymph node without signs of dissemination.
- The child exhibited lymphopenia with reduced T-helper and T-suppressor cells.
Findings:
- Cervical lymphadenitis was diagnosed as a localized Candida albicans infection.
- The immune status showed a decrease in T-cell subsets, suggesting immune modulation by the fungal infection.
- Intravenous fluconazole treatment proved effective.
Implications:
- This case highlights Candida albicans as a potential cause of cervical lymphadenitis in children.
- Localized fungal lymphadenitis may represent an early stage of fungal invasion.
- Understanding the immunological response, including T-cell changes, is crucial for managing such infections.