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Published on: June 30, 2023
Gender differences in patients with heart failure
Anna Strömberg1, Jan Mårtensson
1Department of Cardiology, Heart Centre, Linköping University Hospital, S-581 85 Linköping, Sweden. annst@imv.liu.se
Insights
Men have higher heart failure incidence, but prevalence is similar due to longer female survival. Women are diagnosed later, often with diastolic dysfunction, impacting quality of life differently.
Area of Science:
- Cardiology
- Sex Differences in Medicine
- Public Health
Background:
- Heart failure (HF) affects men and women differently, necessitating a comprehensive understanding of these disparities.
- Existing research highlights variations in epidemiology, diagnosis, treatment, and psychosocial impact.
Purpose of the Study:
- To conduct a literature review examining sex-based differences in heart failure.
- To analyze disparities in epidemiology, etiology, diagnostics, prognosis, treatment, psychosocial factors, and healthcare utilization.
Main Methods:
- Systematic literature review utilizing MEDLINE and CINAHL databases.
- Analysis of 234 abstracts from MEDLINE and 20 from CINAHL focusing on heart failure and gender/sex.
Main Results:
- Men exhibit higher HF incidence, while prevalence is similar due to longer female survival.
- Women diagnosed later with HF, often presenting diastolic dysfunction; age influences treatment and care disparities.
- Distinct psychosocial impacts: men affected by physical/social restrictions, women by inability to support family; women report lower quality of life despite positive illness perception.
Conclusions:
- Significant sex differences in heart failure epidemiology, clinical presentation, and psychosocial impact exist.
- Guidelines and standard care must integrate awareness of these gender-specific disparities.
- Addressing these differences is crucial for improving patient outcomes and quality of life in heart failure management.
Aim:
The aim of this literature review was to review and discuss the differences between men and women with heart failure with regard to epidemiology, aetiology, diagnostics, prognosis, pharmacological and non-pharmacological treatment, and the impact of heart failure on psychosocial factors and healthcare utilisation.
Method:
Two primary health care resources, MEDLINE and CINAHL, were selected to review the current literature. In MEDLINE, 234 abstracts dealing with heart failure and gender/sex were found and in CINAHL, 20 abstracts.
Conclusion:
Men have a higher incidence of heart failure, but the overall prevalence rate is similar in both sexes, since women survive longer after the onset of heart failure. Women tend to be older when diagnosed with heart failure and more often have diastolic dysfunction than men. The extent of sex differences in treatment, hospital cost and quality of care can partly be explained by age differences. The life situations for men and women with heart failure are different. Physical and social restrictions affecting daily life activities are experienced as most bothersome for men, whereas restrictions affecting the possibility to support family and friends are most difficult to accept for women. Women with heart failure ascribe more positive meanings to their illness. Despite this, women seem to experience a lower overall quality of life than men. The known gender differences in patients with heart failure need to be highlighted in guidelines as well as implemented in standard care.
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