Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Immunity and immunization in elderly.

Patrice Bourée1

  • 1Unité des Maladies Parasitaires et Tropicales, Hôpital de Bicêtre 78, rue du Général-Leclerc, 94275 Kremlin-Bicêtre, France. patrice.bouree@bct.ap-hop-paris.fr

Pathologie-Biologie
|November 19, 2003
PubMed
Summary

Elderly travelers face reduced vaccine effectiveness due to immune system changes. However, vaccinations significantly decrease illness and death, making them crucial for older adults, especially for influenza and tetanus.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Institut Alfred-Fournier, 100 years of fighting against STIs].

La Revue du praticien·2024
Same author

[Remain alert for Covid-19 in Mayotte].

Revue francophone des laboratoires : RFL·2020
Same author

La Revue du praticien·2020
Same author

Imported loiasis in France: a retrospective analysis of 167 cases with comparison between sub-Saharan and non sub-Saharan African patients.

BMC infectious diseases·2020
Same author

[Dzaoudzi hospital, medical reference of the Comoros for 150 ans].

La Revue du praticien·2019
Same author

[Strongyloidiasis, a sexually transmitted disease].

Presse medicale (Paris, France : 1983)·2019

Area of Science:

  • Gerontology
  • Immunology
  • Public Health

Background:

  • Increasing life expectancy leads to more elderly travelers.
  • Aging impacts the immune system, specifically T-lymphocytes, reducing vaccine response.
  • Elderly individuals are at higher risk for vaccine-preventable diseases like influenza.

Purpose of the Study:

  • To highlight the challenges of vaccination in the elderly.
  • To emphasize the public health benefits of vaccination for older adults.
  • To recommend essential travel vaccinations for seniors.

Main Methods:

  • Review of immune system changes with aging.
  • Analysis of vaccine seroconversion rates in different age groups.
  • Examination of vaccination impact on morbidity and mortality.

Main Results:

  • Vaccine response (seroconversion) decreases significantly with age, e.g., influenza vaccine response is 11% in those over 80.
  • Despite lower seroconversion, vaccination reduces influenza morbidity by 25% and mortality by 70%.
  • Pneumococcal vaccine is 60% effective, and tetanus vaccination is critical for those over 80.

Conclusions:

  • Vaccination remains vital for elderly travelers despite diminished immune response.
  • Public health initiatives for elderly vaccination yield substantial benefits.
  • Key travel vaccines include those for polio, hepatitis, typhoid, pneumococcus, and tetanus.

Related Experiment Videos