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Updated: Aug 30, 2026

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Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly
Published on: February 6, 2020
Array synthesis of novel lipodepsipeptide
James Siedlecki1, Jason Hill, Ian Parr
1Cubist Pharmaceuticals Inc., 65 Hayden Ave., Lexington, MA 02421, USA.
Bioorganic & Medicinal Chemistry Letters
|November 19, 2003
Abstract:
Synthetic array technology was utilized to rapidly synthesize and analyze a diverse set of reductive alkylation analogues of daptomycin. Analysis of the array suggested the use of polar functionality such as sulfonamides or amide or polar spaces such as piperazine would beneficially affect activity.

