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Updated: Aug 30, 2026

Enhancement of Facial Rejuvenation Through a Combination of 1565 nm Non-Ablative Fractional Laser with 30% Supramolecular Salicylic Acid
Published on: September 27, 2024
Long-pulse 532-nm diode laser for nonablative facial skin rejuvenation
Paul J Carniol1, Sarah Farley, Adam Friedman
1Section of Otolaryngology, Department of Surgery, University of Medicine & Dentistry of New Jersey, Summit 07901, USA.
Objective:
To evaluate the efficacy of a long-pulse 532-nm frequency doubled Nd:YAG laser for nonablative facial skin rejuvenation.
Methods:
Patients received a series of treatments to one side of their periorbital and midfacial region. The opposite side was not treated, and served as a control. An evaluation of the results was performed by the patients and by single-blinded review of digital photographs.
Results:
The patients involved in the study all noted an improvement in their appearance. The single-blinded observers noted a significant improvement in 5 (71%) of the 7 patients. On average, these patients had a 25% improvement in their appearance.
Conclusions:
In this preliminary study, the long-pulse 532-nm Nd:YAG laser was effective for the treatment of photoaging. The patients were pleased with the results, particularly because they were able to obtain an improvement in appearance with minimal discomfort and without any loss of time from their regular activities.

