Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Temporal arteritis without histological changes].

C Bomholt1, O Dietrichson, J U Prause

  • 1Medicinsk afdeling, Sankt Lukas Stiftelsens Hospital, København.

Ugeskrift for Laeger
|October 19, 1992
PubMed
Summary

Giant cell arteritis can affect vision, even with initially normal temporal artery biopsies. Close monitoring of polymyalgia rheumatica patients is crucial for early diagnosis and treatment.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Experimental study of hyaluronic acid gel fillers biodegradation in orbit].

Vestnik oftalmologii·2020
Same author

[Hyaluronic acid gel implants for correction of pathological conditions of the orbit and eyelids].

Vestnik oftalmologii·2018
Same author

[Rare case of primary orbital osteoma].

Vestnik oftalmologii·2016
Same author

[Histopathological study of experimental intrapalpebral injection of hyaluronic acid gel].

Vestnik oftalmologii·2015
Same author

Fungal keratitis - improving diagnostics by confocal microscopy.

Case reports in ophthalmology·2014
Same author

The influence of brightness on functional assessment by mferg: a study on scaffolds used in retinal cell transplantation in pigs.

Stem cells international·2012

Area of Science:

  • Ophthalmology
  • Rheumatology
  • Vascular Inflammation

Background:

  • Giant cell arteritis (GCA) is a systemic vasculitis often affecting older adults.
  • Polymyalgia rheumatica (PMR) is frequently associated with GCA, presenting diagnostic challenges.
  • Ocular involvement in GCA can lead to irreversible vision loss if not promptly treated.

Observation:

  • A patient presented with severe GCA affecting both eyes.
  • Initial symptoms of polymyalgia rheumatica (PMR) were treated with low-dose prednisone.
  • Temporal artery biopsies were negative for GCA, and eye examinations were normal at that time.

Findings:

  • High-dose prednisone treatment led to partial reversal of ocular symptoms in GCA.
  • Delayed diagnosis occurred despite initial negative temporal artery biopsies.
  • The case highlights the potential for GCA to progress insidiously.

Implications:

  • Emphasizes the need for vigilant follow-up in PMR patients, irrespective of initial biopsy results.
  • Suggests that negative temporal artery biopsies do not exclude GCA, especially with evolving symptoms.
  • Underscores the importance of early and aggressive treatment to prevent vision loss in GCA.

Related Experiment Videos