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Updated: Aug 30, 2026

The Power of Simplicity: Sea Urchin Embryos as in Vivo Developmental Models for Studying Complex Cell-to-cell Signaling Network Interactions
Published on: February 16, 2017
Hsp40 is involved in cilia regeneration in sea urchin embryos
Caterina Casano1, Fabrizio Gianguzza, Maria C Roccheri
1Dipartimento di Biologia Cellulare e dello Sviluppo Alberto Monroy, Palermo, Italy. cascate@unipa.it
Abstract:
In a previous paper we demonstrated that, in Paracentrotus lividus embryos, deciliation represents a specific kind of stress that induces an increase in the levels of an acidic protein of about 40 kD (p40). Here we report that deciliation also induces an increase in Hsp40 chaperone levels and enhancement of its ectodermal localization. We suggest that Hsp40 might play a chaperoning role in cilia regeneration.

