Related Experiment Video
Updated: Aug 30, 2026

Intradermal Microdialysis: An Approach to Investigating Novel Mechanisms of Microvascular Dysfunction in Humans
Published on: July 21, 2023
Clinical pharmacology and the management of cardiovascular diseases
1Department of Medicine and Therapeutics, University of Glasgow, Glasgow, Scotland, UK.
Abstract:
Clinical pharmacology contributes to many stages of drug development including discovery, registration, and application in clinical practice. The clinical pharmacologists working in academia, in industries, and with government agencies play an important role in optimizing efficacy and efficiency of drug use. The integration of drug therapy into overall long-term clinical care offers further possibilities. For example, long-term care of cardiovascular and metabolic diseases including hypertension and heart failure have been improved by clinical pharmacologists applying evidence-based practice and rational treatment choices.
Related Concept Videos
Cardiovascular Drugs: Classification based on Therapeutic Indications
Atherosclerosis III: Management
Chronopharmacokinetics: Circadian Rhythms and Influence on Drug Response
The time of drug administration is an important factor to consider, as it can influence the toxic dose of a drug. For example, a study conducted by Prins et al. in 1997 examined the effects of the timing of...
Cardiomyopathy V: Interprofessional Care
Antianginal Drugs: Calcium Channel Blockers and Ranolazine
CCBs, a diverse class that includes dihydropyridines (nifedipine) and diphenylalkylamines (verapamil and diltiazem), exert their effect by blocking calcium channels in cardiac and smooth muscle cells. This...
Pharmacodynamics: Overview and Principles
Most drugs' effects result from their interactions with drug receptors or targets within the body. These interactions trigger specific responses at the cellular or systemic level. Drug receptors can be found on the surfaces of cells or within...
