[Rare seminoma metastasis to the corpus spongiosum and urethra]

Area of Science:

• Urology
• Oncology
• Radiotherapy

Background:

• Anaplastic seminoma is a rare subtype of testicular germ cell tumor, comprising 5-10% of all seminomas.
• Metastatic patterns of anaplastic seminoma typically mirror those of classic seminoma.
• Penile metastases from testicular tumors are uncommon.

Observation:

• A patient with an oligophrenic presentation of seminoma (pT1 stage) developed an unusual metastasis.
• The metastasis localized to the corpus spongiosum and penile urethra, a rare site for seminoma spread.
• The patient's intellectual disability was noted as a characteristic.

Findings:

• The penile metastasis was treated with local external radiotherapy.
• The treatment resulted in successful long-term tumor remission.
• A follow-up period of 4 years confirmed sustained remission.

Implications:

• This case demonstrates the efficacy of radiotherapy in managing rare extragonadal seminoma metastases.
• It expands the understanding of potential metastatic sites for anaplastic seminoma.
• Highlights the importance of considering radiotherapy for localized penile metastases in testicular cancer patients.