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Fast mapping of protein-protein interfaces by NMR spectroscopy

Michael L Reese1, Volker Dötsch

  • 1Graduate Group in Biophysics, University of California-San Francisco, San Francisco, CA 94143, USA.

Journal of the American Chemical Society
|November 20, 2003
PubMed

Abstract:

Identifying the interface of protein complexes can represent a difficult task in structural biology. Here, we report a method for the fast mapping of interfaces of protein complexes by NMR without the need for the assignments of the proteins involved.

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