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[Infective endocarditis in the elderly].

J M Cruz1, R Martínez, M García

  • 1Servicio de Medicina Interna, Hospital Cristal-Piñor, Ourense.

Anales De Medicina Interna (Madrid, Spain : 1984)
|November 20, 2003
PubMed
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Age does not negatively impact infective endocarditis (IE) prognosis. Elderly patients with IE showed similar outcomes and treatment frequency compared to younger adults, indicating age alone is not a poor prognostic factor.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Geriatrics

Background:

  • The impact of aging on infective endocarditis (IE) presentation and prognosis remains unclear.
  • Investigating IE in elderly versus younger adults is crucial for understanding age-related differences.

Purpose of the Study:

  • To compare epidemiologic, clinical, and bacteriological characteristics of IE in elderly (>65 years) versus younger (20-64 years) adult patients.
  • To analyze the influence of age on IE diagnosis, treatment, and outcomes.

Main Methods:

  • Retrospective study of non-intravenous drug user IE patients from 1990-2000.
  • Utilized Duke criteria to compare 46 elderly IE episodes with 46 younger adult IE episodes.
  • Assessed diagnostic methods like echocardiography and treatment approaches.

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Main Results:

  • No significant differences in diagnosis delay, infection source, positive blood cultures, or IE evolution between age groups.
  • Elderly patients had more predisposing risk factors, reducing transthoracic echocardiography sensitivity.
  • Transesophageal echocardiography improved IE diagnosis in 37.2% of elderly patients.
  • Similar surgical therapy rates and no significantly higher mortality in the elderly (19.5%) versus younger adults (10.8%).

Conclusions:

  • Age is not an independent poor prognostic factor for infective endocarditis.
  • Early and aggressive treatment should not be withheld from elderly IE patients based solely on age.