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Updated: Aug 30, 2026

Metabolomic Analysis of Barley by Gas Chromatography/Mass Spectrometry
Published on: November 8, 2024
Effects of barley intake on glucose tolerance, lipid metabolism, and bowel function in women
Jue Li1, Takashi Kaneko, Li Qiang Qin
1Department of Environmental Health, School of Medicine, University of Yamanashi, Tamaho, Yamanashi, Japan.
Objective:
The low consumption of grains that are rich sources of dietary fiber may be associated with the increasing prevalence of chronic diseases. This study was conducted to observe the effects of high barley (high-fiber diet) intake on glucose tolerance, lipid metabolism, and bowel function in healthy women.
Methods:
Ten women volunteers (20.4 +/- 1.3 y, 19.2 +/- 2.0 kg/m2) signed informed consents and received a standard diet and a barley diet, with each diet for a period of 4 wk with a 1-mo interval (randomized cross-over design). Both diets contained the same amounts of carbohydrate, fat, and protein.
Results:
The barley intake significantly lowered plasma total and low-density lipoprotein cholesterol concentrations and reduced plasma triacylglycerol concentration. Barley intake also increased stool volume. There was no significant difference in glucose tolerance between diet regimens.
Conclusions:
This study demonstrated that barley intake has beneficial effects on lipid metabolism and bowel function and suggests that the intake of a high-fiber food, i.e., barley, should be recommended to prevent chronic diseases.
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