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Relationship between some biological parameters and plasma testosterone in institutionalized aging men
J-L Thomas1, B T Quang, E Ochsenbein
1Service de Gérontologie, Centre Hospitalier Emile Roux, Limeil Brevannes France.
The Journal of Nutrition, Health & Aging
|November 20, 2003
Summary
Elderly men with chronic illness showed low testosterone levels. A significant inverse correlation was found between testosterone and fasting blood glucose, suggesting a link persists in institutionalized populations.
Area of Science:
- Gerontology
- Endocrinology
- Clinical Chemistry
Background:
- Circulating testosterone levels naturally decline with age in men.
- This age-related decline is associated with various biological changes.
Purpose of the Study:
- To examine the relationship between total testosterone and key laboratory blood tests.
- Focus on elderly institutionalized men with chronic illnesses.
Main Methods:
- Analysis of total testosterone levels.
- Correlation with fasting blood glucose, total cholesterol, total proteins, albumin, and red blood cells (RBC).
- Study population: elderly institutionalized men (mean age 82.7 years).
Main Results:
- Significantly low total testosterone levels were observed in the study sample.
- A strong inverse correlation between testosterone and fasting blood glucose was identified.
- Testosterone showed positive correlations with hematocrit and albumin levels.
Conclusions:
- The inverse relationship between testosterone and fasting blood glucose is present in institutionalized elderly men, similar to healthy populations.
- The association between testosterone and other biological parameters warrants further investigation.