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Published on: November 1, 2015
The relationship between serum ferritin levels and disease activity in systemic lupus erythematosus
E Beyan1, C Beyan, A Demirezer
1Department of Internal Medicine, Numune Education and Research Hospital, Ankara, Turkey.
Objective:
The aim of this study is to investigate the relationship between serum ferritin levels and disease activity in patients with systemic lupus erythematosus (SLE).
Methods:
Serum ferritin levels of 72 SLE patients were measured. The SLE patients were subdivided into two groups according to SLE disease activity index (SLEDAI) as < or = 10 and > or = 11. The results were compared with 31 patients with rheumatoid arthritis (RA). 36 patients among 72 with SLE were evaluated before and after treatment.
Results:
Serum levels of ferritin in SLE patients were higher than RA patients (p < 0.001). There was a significant difference in ferritin levels before and after treatment. The levels of ferritin in SLE were positively correlated with SLEDAI scores. Patients with SLEDAI scores > or = 11 had significantly higher serum ferritin levels.
Conclusion:
Serum ferritin levels may be a useful marker of disease activity in SLE patients.
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