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[Symptomatic left ventricular dysfunction and Behçet disease. Report of 2 cases].

A Scheuble1, O Belliard, S Robinet

  • 1Hôpital Saint-Antoine, service de cardiologie, 184, rue du Faubourg Saint-Antoine, 75571 Paris.

Archives Des Maladies Du Coeur Et Des Vaisseaux
|November 25, 2003
PubMed
Summary

Behçet

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Area of Science:

  • Cardiology
  • Rheumatology
  • Pathology

Background:

  • Behçet's disease, a systemic vasculitis, can affect cardiac structures in 1-6% of cases.
  • Cardiac involvement includes pericardial, coronary, and myocardial disease.
  • Left ventricular dysfunction, presenting as dilated cardiomyopathy, is a potential complication.

Observation:

  • Two cases of Behçet's disease with symptomatic left ventricular dysfunction are presented.
  • One case demonstrated dilated cardiomyopathy with normal coronary arteries, suggesting inflammatory myocarditis.
  • Echocardiographic studies indicate underdiagnosis of myocardial disease in Behçet's patients.

Findings:

  • Left ventricular dysfunction can occur in Behçet's disease, independent of coronary artery disease.

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  • Myocardial inflammation (myocarditis) is a potential cause of cardiac dysfunction.
  • 20-35% of asymptomatic Behçet's patients exhibit left ventricular diastolic dysfunction.

    • Implications:

    • Early detection of myocardial involvement in Behçet's disease is crucial.
    • Assessing left ventricular diastolic function aids in timely diagnosis of cardiac complications.
    • This highlights the importance of comprehensive cardiac evaluation in Behçet's disease management.